Turk J Hematol. 2016; 33(3): 248-250 | DOI: 10.4274/tjh.2015.0259

Radiation-Induced Tumor Lysis Syndrome in Chronic Lymphocytic Leukemia

Ali Alkan¹, Tuğçe Kütük², Ebru Karcı¹, Arzu Yaşar¹, Ayşe Hiçsönmez², Güngör Utkan^1
1Ankara University Faculty of Medicine, Department of Medical Oncology, Ankara, Turkey
²Ankara University Faculty of Medicine, Department of Radiation Oncology, Ankara, Turkey

Tumor lysis syndrome (TLS) is an important oncological emergency that is usually observed with hematological malignancies and rarely with solid tumors. It can be induced either by therapy or spontaneously. Radiotherapy-induced TLS has been rarely reported in the literature. Here we present a patient with a diagnosis of metastatic prostate cancer and chronic lymphocytic leukemia complicated with TLS during palliative radiotherapy.

Keywords: Chronic lymphocytic leukemia, Radiation, Tumor lysis syndrome

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Kronik Lenfositik Lösemide Radyasyon İlişkili Tümör Lizis Sendromu

Ali Alkan¹, Tuğçe Kütük², Ebru Karcı¹, Arzu Yaşar¹, Ayşe Hiçsönmez², Güngör Utkan^1
1Ankara University Faculty of Medicine, Department of Medical Oncology, Ankara, Turkey
²Ankara University Faculty of Medicine, Department of Radiation Oncology, Ankara, Turkey

Tümör lizis sendromu (TLS) sıklıkla hematolojik malignitelerde görülen, nadiren solid tümörlerde karşımıza çıkabilen bir onkolojik acildir. Tedavi ilişkili olabileceği gibi spontan olarak da ortaya çıkabilir. Radyasyon ilişkili TLS literatürde nadiren bildirilmiştir. Burada, kronik lenfositik lösemi ve prostat kanseri tanısıyla izlenen hastada palyatif radyoterapi ile indüklenen TLS olgusu sunulmaktadır.

Anahtar Kelimeler: Kronik lenfositik lösemi, Radyasyon, Tümör lizis sendromu

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