ISSN: 1300-7777 E-ISSN: 1308-5263
Hypereosinophilia as a Preclinical Sign of Tongue Squamous Cell Cancer in a Gastric Cancer Patient with Complete Remission [Turk J Hematol]
Turk J Hematol. 2003; 20(2): 107-110

Hypereosinophilia as a Preclinical Sign of Tongue Squamous Cell Cancer in a Gastric Cancer Patient with Complete Remission

Hasan Şenol Coşkun1, Özlem Er2, Fatih Tanrıverdi2, Mustafa Altınbaş2
1Department Of Internal Medicine, Süleyman Demirel University Medical Faculty, Isparta, Turkey
2Erciyes University Medical Faculty M.k. Dedeman Oncology Hospital, Kayseri, Turkey

Although parasitic infestations and allergic disorders are the most common causes of eosinophilia it may also occompany malignant diseases. Many studies suggested that eosinophilia is related to tumor dissemination or necrosis. We are presenting a case; 10 months after gastric carcinoma operation who had severe eosinophilia with bone marrow and skin infiltration that gave response to steroid therapy. After three months, tongue squamous cell carsinoma as a second malignancy occurred in our patient that the eosinophilia could be the preclinical sign of the second cancer.

Keywords: Gastric cancer, Adenocarcinoma, Eosinophilia, Tongue cancer, Squamous carcinoma.


Remisyonda Gastrik Kanseri Olan Bir Hastada Dilde Skuamöz Hücreli Kanserin Belirtisi Olarak Hipereozinofili

Hasan Şenol Coşkun1, Özlem Er2, Fatih Tanrıverdi2, Mustafa Altınbaş2
1Department Of Internal Medicine, Süleyman Demirel University Medical Faculty, Isparta, Turkey
2Erciyes University Medical Faculty M.k. Dedeman Oncology Hospital, Kayseri, Turkey

Her ne kadar allerjik ve paraziter hastalıklar eozinofilinin en sık sebepleri ise de, eozinofili malign hastalıklara eşlik edebilir. Çalışmalar bu durumda, eozinofilinin nedeninin tümörün yayılması veya nekrozu olduğunu göstermektedir. Bu makalede sunduğumuz olgu gastrik kanser ameliyatından 10 ay sonra kemik iliği ve ciltte ciddi eozinofili ve eozinofili infiltrasyonu göstermiş ve steroide yanıt vermiştir. Üç ay sonra ikincil malignite olarak dil skuamöz hücreli kanseri geliştiren hastada, eozinofilinin ikincil kanserin erken bulgusu olarak görüldüğünü düşünmekteyiz.

Anahtar Kelimeler: Gastrik kanser, Adenokanser, Eozinofili, Dil kanseri, Skuamöz kanser. Turk J Haematol


Hasan Şenol Coşkun, Özlem Er, Fatih Tanrıverdi, Mustafa Altınbaş. Hypereosinophilia as a Preclinical Sign of Tongue Squamous Cell Cancer in a Gastric Cancer Patient with Complete Remission. Turk J Hematol. 2003; 20(2): 107-110, Türkiye


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