ISSN: 1300-7777 E-ISSN: 1308-5263
Fibrinogen concentration: A marker of cardiovascular disorders in Nigerians [Turk J Hematol]
Turk J Hematol. 2007; 24(1): 18-22

Fibrinogen concentration: A marker of cardiovascular disorders in Nigerians

Olutayo Ifedayo Ajayi, Adekunle Ademola Famodu, Efosa Oviasu
Departments Of Physiology, University Of Benin, Benin City, Edo State, Nigeria

Fibrinogen, one of the most hemorheologically active plasma proteins, is associated with several cardiovascular risk factors, and the plasma concentration can alter dramatically during acute phase response and in a wide variety of clinical conditions. We have assessed fibrinogen levels in some known cardiovascular disorders, during usage of contraceptive pills, acute phase conditions and pregnancy. Our results from patients with various disease conditions indicate that fibrinogen levels are in the pathological range and are significantly higher than in healthy controls (p<0.001). It is concluded that although Africans have low predisposition to thrombosis, they may well be pre-disposed to abnormal fibrin formation which could lead to various thromboembolic complications.

Keywords: Fibrinogen, cardiovascular risk factor, Nigerians


Olutayo Ifedayo Ajayi, Adekunle Ademola Famodu, Efosa Oviasu. Fibrinogen concentration: A marker of cardiovascular disorders in Nigerians. Turk J Hematol. 2007; 24(1): 18-22

Corresponding Author: Olutayo Ifedayo Ajayi, Nigeria


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Impact Factor (2016) = 0.686