ISSN: 1300-7777 E-ISSN: 1308-5263
Anaplastic T-Cell Lymphoma Associated with Hemophagocytic Syndrome: A Case Report [Turk J Hematol]
Turk J Hematol. 2003; 20(2): 101-106

Anaplastic T-Cell Lymphoma Associated with Hemophagocytic Syndrome: A Case Report

Fahri Şahin1, Münir Buke2, Güray Saydam1, Devrim Bozkurt1, Saliha Soydan3
1Division Of Hematology, Department Of Internal Medicine, Ege University Medical School, İzmir, Turkey
2Department Of Clinical Microbiology And Infection Disease, Ege University Medical School, İzmir, Turkey
3Department Of Pathology, Ege University Medical School, İzmir, Turkey

Hemophagocytic syndrome (HPS) is mostly associated with malignant and infectious diseases. The causes and prognosis of this clinical syndrome depend on the underlying disease. And also treatment of this disease must be arranged according to the underlying causes. While non-Hodgkin’s lymphomas (NHL) associated with HPS has been frequently observed, anaplastic T-cell NHL associated with HPS has been rarely reported. In this article we report a case of Ki-1+ anaplastic T-cell lymphoma associated with HPS in a 16-year-old woman who presented with fever and lymphadenopathy.

Keywords: Anaplastic T-cell lymphoma, Hemophagocytic syndrome.


Bir Olgu: Hemofagositik Sendroma Eşlik Eden Anaplastik T-hücreli Lenfoma

Fahri Şahin1, Münir Buke2, Güray Saydam1, Devrim Bozkurt1, Saliha Soydan3
1Division Of Hematology, Department Of Internal Medicine, Ege University Medical School, İzmir, Turkey
2Department Of Clinical Microbiology And Infection Disease, Ege University Medical School, İzmir, Turkey
3Department Of Pathology, Ege University Medical School, İzmir, Turkey

Hemofagositik sendrom (HPS) sıklıkla malign ve infeksiyöz hastalıklara eşlik eder. Bu klinik sendromun sebep ve prognozu altta yatan hastalığa bağlıdır. Tedavi de altta yatan hastalığa göre düzenlenmelidir. HSP’ye eşlik eden non-Hodgkin lenfoma’ya sık rastlanırken, anaplastik T-hücreli lenfoma çok seyrek bildirilmiştir. Bu yazıda ateş ve lenfadenopati ile gelen 16 yaşında bir kadında Ki-1+ anaplastik T-hücreli lenfomaya eşlik eden HPS sunulmaktadır.

Anahtar Kelimeler: Anaplastik T-hücreli lenfoma, Hemofagositik sendrom.


Fahri Şahin, Münir Buke, Güray Saydam, Devrim Bozkurt, Saliha Soydan. Anaplastic T-Cell Lymphoma Associated with Hemophagocytic Syndrome: A Case Report. Turk J Hematol. 2003; 20(2): 101-106

Corresponding Author: Güray Saydam, Türkiye


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