Trace Element Analyses (Zinc and Selenium) in Pediatric Malignant LymphomasAyhan O. Çavdar1, Emel Ünal1, Emel Babacan1, Sevgi Gözdaşoğlu2, Gülsan Yavuz1, K. Mengübaş1, Ali Pamir1, Nurdan Taçyıldız11Pediatric Hematology And Oncology Research Center Of Ankara University, Ankara, Turkey
2Satellite Trace Element Center Of Unesco İn Ankara, Turkey
Ninetysix untreated patients with Malignant lymphoma’s, 81 Hodgkin’s disease and 15 Burkitt’s lymphoma were studied for zinc (Zn) and selenium (Se) status. Plasma and hair Zn, and Se levels were measured by atomic absorption spectrophotometry. Chronic Zn and Se deficiencies (low plasma and low hair Zn and Se levels together) were found to be associated with Malignant lymphoma’s in Turkish children. This was most likely due to poor “nutritional environment” of the patients since majority of the Malignant lymphoma cases were from low socioeconomic class. Supplemention of the patients with physiological doses of Zn and Se, in addition to standard chemo radiotherapy regimen was proposed. Keywords: Zinc and selenium, Malignant lymphoma.
Ayhan O. Çavdar, Emel Ünal, Emel Babacan, Sevgi Gözdaşoğlu, Gülsan Yavuz, K. Mengübaş, Ali Pamir, Nurdan Taçyıldız. Trace Element Analyses (Zinc and Selenium) in Pediatric Malignant Lymphomas. Turk J Hematol. 2002; 19(2): 239-244
Corresponding Author: Ayhan O. Çavdar, Türkiye |
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