ISSN: 1300-7777 E-ISSN: 1308-5263
Coexistence of Two Prothrombotic Mutations, Factor V 1691 G-A and Prothrombin 20210 G-A, and the Risk of Thrombosis in Turkish Population [Turk J Hematol]
Turk J Hematol. 2003; 20(1): 31-33

Coexistence of Two Prothrombotic Mutations, Factor V 1691 G-A and Prothrombin 20210 G-A, and the Risk of Thrombosis in Turkish Population

Nejat Akar, Erkan Yılmaz, Ece Akar
The Pediatric Molecular Genetics Department Of The Ankara University, Ankara, Turkey

This report summarizes the coexistence of two mutations; Factor V 1691 G-A and prothrombin 20210 G-A in Turkish population and emphasises on the point that, this coexistence increases the risk of thrombosis in such patients. In thrombophilia screening programs, these two variants should be included, particularly in Turkish population.

Keywords: Factor V gene, Prothrombin gene, Thrombosis.


İki Protrombotik Mutasyonun (Faktör V 1691 G-A ve Protrombin 20210 G-A) Birlikteliği ve Türk Toplumunda Tromboz Riski

Nejat Akar, Erkan Yılmaz, Ece Akar
The Pediatric Molecular Genetics Department Of The Ankara Universitesi, Ankara, Turkiye

Bu yazıda Türk toplumunda Faktör V 1691 G-A ve protrombin 20210 G-A mutasyonlarının birarada bulunma sıklığı özetlenmekte ve bu birlikteliğin tromboz riskini arttırdığı vurgulanmaktadır. Türk toplumu trombofili tarama programları için bu iki varyant eklenmelidir.

Anahtar Kelimeler: Faktör V geni, Protrombin geni, Tromboz. Turk J Haematol


Nejat Akar, Erkan Yılmaz, Ece Akar. Coexistence of Two Prothrombotic Mutations, Factor V 1691 G-A and Prothrombin 20210 G-A, and the Risk of Thrombosis in Turkish Population. Turk J Hematol. 2003; 20(1): 31-33

Corresponding Author: Nejat Akar, Türkiye


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