ISSN: 1300-7777 E-ISSN: 1308-5263
The Incidence of Hepatitis G Virus in Patients with Hematological Malignancies: The Relationship to the Number of Blood and Blood Products Transfusions [Turk J Hematol]
Turk J Hematol. 2000; 17(2): 67-71

The Incidence of Hepatitis G Virus in Patients with Hematological Malignancies: The Relationship to the Number of Blood and Blood Products Transfusions

Ramazan İdilman1, Celalettin Üstün2, Önder Aslan2, Muhit Özcan2, Mutlu Arat2, Hakan Bozkaya1, Mithat Bozdayı3, Tijen Şengezer3, Özden Uzunalimoğlu3, Abdulkadir Dökmeci1, Osman İlhan2, Haluk Koç2, Hamdi Akan2
1Department Of Gastroenterology, Medical School, University Of Ankara, Ankara, Turkey
2Department Of Hematology, Medical School, University Of Ankara, Ankara,turkey
3Hepatology Institute, University Of Ankara, Ankara, Turkey

The hepatitis G virus has been detected in patients with post-transfusion hepatitis. The precise transmission rate of the hepatitis G virus is not clear. This study aims to investigate the transmission rate of HGV and the relationship between the number of blood transfusions and the blood products used in multitransfused patients with hematological malignancies. Serum samples were obtained from 80 patients with hematologic malignancies hospitalized between January 1997 and December 1998 at Ibn’i Sina Hospital, University of Ankara. The patients were divided into three groups according to transfusion numbers. Group A received between 0 and 10 units of blood and blood products, Group B received 10-20 units, and Group C received more than 20 units. All patients received blood and blood products for a median of 6.8 Units/whole life. The hepatitis G virus was detected using the reverse transcription polymerase chain reaction. Of the eighty patients, four (5.0 %) were HBs-Ag positive, one (1.25%) was Anti-HCV positive, and one (1.25%) was HGV-RNA positive. Multiple blood transfusions may be an important risk factor for transmission-transmitted viral infections, but based upon the present experience, there is no significant relationship between the number of blood transfusions and blood products and the transmission rate of HGV infection in patients with hematological malignancies.

Keywords: Hepatitis G virus, Transfusion, Hematological malignancies, Blood-borne infection.


Ramazan İdilman, Celalettin Üstün, Önder Aslan, Muhit Özcan, Mutlu Arat, Hakan Bozkaya, Mithat Bozdayı, Tijen Şengezer, Özden Uzunalimoğlu, Abdulkadir Dökmeci, Osman İlhan, Haluk Koç, Hamdi Akan. The Incidence of Hepatitis G Virus in Patients with Hematological Malignancies: The Relationship to the Number of Blood and Blood Products Transfusions. Turk J Hematol. 2000; 17(2): 67-71

Corresponding Author: Ramazan İdilman, Türkiye


TOOLS
Full Text PDF
Print
Download citation
RIS
EndNote
BibTex
Medlars
Procite
Reference Manager
Share with email
Share
Send email to author

Similar articles
PubMed
Google Scholar


 



Impact Factor (2017) = 0.650