ISSN: 1300-7777 E-ISSN: 1308-5263
Characteristics of “Early Type-I Pattern” (0-6 years) Hodgkin’s Disease in Turkish Children [Turk J Hematol]
Turk J Hematol. 2002; 19(1): 55-62

Characteristics of “Early Type-I Pattern” (0-6 years) Hodgkin’s Disease in Turkish Children

Ayhan O. Çavdar, Sevgi Gözdaşoğlu, Gülsan Yavuz, Emel Ünal, Ali Pamir, Nurdan Taçyıldız, Emel Babacan
Pediatric Hematology And Oncology Research Center, University Of Ankara, Ankara, Turkey

The clinico-epidemiologic characteristics of 54 children with HD in 0-6 years of age group were retrospectively
analyzed. This group represented 27% of 200 HD cases observed in our center and was named
as early type-I pattern HD. The association of EBV with HD was also shown by serologic and immunohistochemical
methods (LMP1) in these very young Turkish patients. T-cell immune deficiency,
cytokine imbalance and Zn deficiency were additional findings found in these patients. This series seems
to be the largest one studying early type-I HD, by several aspects.

Keywords: Type-I pattern Hodgkin’s disease, Turkish children.


Ayhan O. Çavdar, Sevgi Gözdaşoğlu, Gülsan Yavuz, Emel Ünal, Ali Pamir, Nurdan Taçyıldız, Emel Babacan. Characteristics of “Early Type-I Pattern” (0-6 years) Hodgkin’s Disease in Turkish Children. Turk J Hematol. 2002; 19(1): 55-62

Corresponding Author: Ayhan O. Çavdar, Türkiye


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