B-Cell Lymphoma Presenting with Extensive Cutaneous Involvement

Ta�k�ran, Beng�r; S�zmen, B�lent; Payz�n, Bahriye; Bener, Sadi; Aslan, Leyla

B-Cell Lymphoma Presenting with Extensive Cutaneous Involvement [Turk J Hematol]

Turk J Hematol. 2003; 20(4): 241-245

B-Cell Lymphoma Presenting with Extensive Cutaneous Involvement

Beng�r Ta�k�ran¹, B�lent S�zmen¹, Bahriye Payz�n², Sadi Bener³, Leyla Aslan¹
¹3rd Clinic Of Internal Medicine Izmir Atat�rk Education Hospital, �zmir, Turkey
²Department Of Haematology Izmir Atat�rk Education Hospital, �zmir, Turkey
³Department Of Pathology Izmir Atat�rk Education Hospital, Izmir, Turkey

Cutaneous lymphomas tend to be of T-cell origin, less commonly of B-cell origin. We report a 68-year-old male patient suffering from extensive cutaneous nodules which were found to be B-cell large cell lymphoma in nature. Our case is a good example to unexpected cutaneous involvement of diffuse large cell lymphomas. It may be debated whether it is a primary cutaneous lymphoma or cutaneous involvement of a systemic lymphoma. The case differs from other primary cutaneous lymphomas in the clinical course and in the pathologic and immunohistochemical features. Systemic B-cell lymphomas may also involve the skin. We think that our case demands attention because systemic B-cell lymphomas with such a great skin involvement is not reported in the literature before.

Keywords: Lymphoma, Large-Cell, B-Cell.

Yayg�n Cilt Tutulumu ile Gelen B-H�creli Lenfoma

Beng�r Ta�k�ran¹, B�lent S�zmen¹, Bahriye Payz�n², Sadi Bener³, Leyla Aslan¹
¹3rd Clinic Of Internal Medicine �zmir Atat�rk Education Hospital, �zmir, Turkey
²Department Of Haematology �zmir Atat�rk Education Hospital, �zmir, Turkey
³Department Of Pathology �zmir Atat�rk Education Hospital, �zmir, Turkey

K�tan�z lenfomalar genellikle T-lenfositlerinden k�ken al�r. Daha nadir olarak B-h�cre k�kenlidirler. Hastanemize yayg�n deri ve deri alt� nod�lleri ile ba�vuran 68 ya��nda erkek bir hastan�n patolojik olarak B-h�creli lenfoma oldu�unu belirledik. Dif�z b�y�k h�creli lenfomalar�n beklenmedik deri tutulumunun bir �rne�i olarak ilgi �eken vakam�z ayn� zamanda primer k�tan�z lenfomalardan da klinik seyir, patolojik ve imm�nhistokimyasal �zellikleri a��s�ndan da farkl�l�k g�stermektedir. Literat�rde bu derece dermal tutulum g�steren sistemik B-h�creli lenfoma bulunmad�� i�in dikkat �eken bir olgu oldu�unu d��nmekteyiz.

Anahtar Kelimeler: B�y�k h�creli lenfoma, B-h�cre.

Beng�r Ta�k�ran, B�lent S�zmen, Bahriye Payz�n, Sadi Bener, Leyla Aslan. B-Cell Lymphoma Presenting with Extensive Cutaneous Involvement. Turk J Hematol. 2003; 20(4): 241-245

Corresponding Author: Beng�r Ta�k�ran, T�rkiye

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