ISSN: 1300-7777 E-ISSN: 1308-5263
B-Cell Lymphoma Presenting with Extensive Cutaneous Involvement [Turk J Hematol]
Turk J Hematol. 2003; 20(4): 241-245

B-Cell Lymphoma Presenting with Extensive Cutaneous Involvement

Bengür Taşkıran1, Bülent Sözmen1, Bahriye Payzın2, Sadi Bener3, Leyla Aslan1
13rd Clinic Of Internal Medicine Izmir Atatürk Education Hospital, İzmir, Turkey
2Department Of Haematology Izmir Atatürk Education Hospital, İzmir, Turkey
3Department Of Pathology Izmir Atatürk Education Hospital, Izmir, Turkey

Cutaneous lymphomas tend to be of T-cell origin, less commonly of B-cell origin. We report a 68-year-old male patient suffering from extensive cutaneous nodules which were found to be B-cell large cell lymphoma in nature. Our case is a good example to unexpected cutaneous involvement of diffuse large cell lymphomas. It may be debated whether it is a primary cutaneous lymphoma or cutaneous involvement of a systemic lymphoma. The case differs from other primary cutaneous lymphomas in the clinical course and in the pathologic and immunohistochemical features. Systemic B-cell lymphomas may also involve the skin. We think that our case demands attention because systemic B-cell lymphomas with such a great skin involvement is not reported in the literature before.

Keywords: Lymphoma, Large-Cell, B-Cell.


Yaygın Cilt Tutulumu ile Gelen B-Hücreli Lenfoma

Bengür Taşkıran1, Bülent Sözmen1, Bahriye Payzın2, Sadi Bener3, Leyla Aslan1
13rd Clinic Of Internal Medicine İzmir Atatürk Education Hospital, İzmir, Turkey
2Department Of Haematology İzmir Atatürk Education Hospital, İzmir, Turkey
3Department Of Pathology İzmir Atatürk Education Hospital, İzmir, Turkey

Kütanöz lenfomalar genellikle T-lenfositlerinden köken alır. Daha nadir olarak B-hücre kökenlidirler. Hastanemize yaygın deri ve deri altı nodülleri ile başvuran 68 yaşında erkek bir hastanın patolojik olarak B-hücreli lenfoma olduğunu belirledik. Difüz büyük hücreli lenfomaların beklenmedik deri tutulumunun bir örneği olarak ilgi çeken vakamız aynı zamanda primer kütanöz lenfomalardan da klinik seyir, patolojik ve immünhistokimyasal özellikleri açısından da farklılık göstermektedir. Literatürde bu derece dermal tutulum gösteren sistemik B-hücreli lenfoma bulunmadığı için dikkat çeken bir olgu olduğunu düşünmekteyiz.

Anahtar Kelimeler: Büyük hücreli lenfoma, B-hücre.


Bengür Taşkıran, Bülent Sözmen, Bahriye Payzın, Sadi Bener, Leyla Aslan. B-Cell Lymphoma Presenting with Extensive Cutaneous Involvement. Turk J Hematol. 2003; 20(4): 241-245

Corresponding Author: Bengür Taşkıran, Türkiye


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