ISSN: 1300-7777 E-ISSN: 1308-5263
Radiation-Induced Tumor Lysis Syndrome in Chronic Lymphocytic Leukemia [Turk J Hematol]
Turk J Hematol. 2016; 33(3): 248-250 | DOI: 10.4274/tjh.2015.0259  

Radiation-Induced Tumor Lysis Syndrome in Chronic Lymphocytic Leukemia

Ali Alkan1, Tuğçe Kütük2, Ebru Karcı1, Arzu Yaşar1, Ayşe Hiçsönmez2, Güngör Utkan1
1Ankara University Faculty of Medicine, Department of Medical Oncology, Ankara, Turkey
2Ankara University Faculty of Medicine, Department of Radiation Oncology, Ankara, Turkey

Tumor lysis syndrome (TLS) is an important oncological emergency that is usually observed with hematological malignancies and rarely with solid tumors. It can be induced either by therapy or spontaneously. Radiotherapy-induced TLS has been rarely reported in the literature. Here we present a patient with a diagnosis of metastatic prostate cancer and chronic lymphocytic leukemia complicated with TLS during palliative radiotherapy.

Keywords: Chronic lymphocytic leukemia, Radiation, Tumor lysis syndrome


Kronik Lenfositik Lösemide Radyasyon İlişkili Tümör Lizis Sendromu

Ali Alkan1, Tuğçe Kütük2, Ebru Karcı1, Arzu Yaşar1, Ayşe Hiçsönmez2, Güngör Utkan1
1Ankara University Faculty of Medicine, Department of Medical Oncology, Ankara, Turkey
2Ankara University Faculty of Medicine, Department of Radiation Oncology, Ankara, Turkey

Tümör lizis sendromu (TLS) sıklıkla hematolojik malignitelerde görülen, nadiren solid tümörlerde karşımıza çıkabilen bir onkolojik acildir. Tedavi ilişkili olabileceği gibi spontan olarak da ortaya çıkabilir. Radyasyon ilişkili TLS literatürde nadiren bildirilmiştir. Burada, kronik lenfositik lösemi ve prostat kanseri tanısıyla izlenen hastada palyatif radyoterapi ile indüklenen TLS olgusu sunulmaktadır.

Anahtar Kelimeler: Kronik lenfositik lösemi, Radyasyon, Tümör lizis sendromu


Ali Alkan, Tuğçe Kütük, Ebru Karcı, Arzu Yaşar, Ayşe Hiçsönmez, Güngör Utkan. Radiation-Induced Tumor Lysis Syndrome in Chronic Lymphocytic Leukemia. Turk J Hematol. 2016; 33(3): 248-250

Corresponding Author: Ali Alkan, Türkiye


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